BRCA2 and cancer: In the Ontario Pancreas Cancer Registry study [26], the germline DNA from 290 patients with varying degrees of family history was sequenced using a panel of 13 genes (APC, ATM, BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, STK11, and TP53).