Another study highlighted the potential prognostic significance of lncRNA showing that the lncRNA deleted in lymphocytic leukemia 1 (DLEU1) may in part function as a tumor suppressor gene and was associated with treatment resistance in children and adolescents with BL in a miR-15a/16-1 dependent manner [122] (Table 2). The gene discussed is DLEU1; the disease is Burkitt lymphoma.