IFNG and Miyoshi myopathy: This impaired response of MM patients is often associated with a downregulation or loss of HLA class I antigens and/or components of the HLA class I antigen-processing machinery (APM), leading to evasion from immune surveillance [6,7,8], disease progression and/or poor patients’ outcome [9,10], but their expression could be frequently upregulated by interferon (IFN)-α and IFN-γ [11,12].