CDK9 and familial pancreatic carcinoma: Further, CDK9 was found to regulate the expression of c-Myc and Mcl1, which are known to promote cell proliferation and survival, and CDK9 inhibition has been shown to interfere with c-Myc function in K-Ras mutant pancreatic cancers and hematologic cancer cells [41,42,43,44,45,46,47,48,49].