Four non-mediating genes were recognized, namely: GRAM domain containing 1B (involved in cholesterol metabolism and oncogenesis), KH domain containing 3 like (involved in oncogenesis), subcortical maternal complex member (implicated in maternal effect of unknown exact function), unc-51 like kinase 4 (associated to bipolar disorder and schizophrenia). Here, GRAMD1B is linked to bipolar disorder.