Western blot analysis revealed that K16 protein was more abundant in carcinoma cells of the basal-like A and normal-like subtypes that also express CDH1 and VIM, while K16 expression was completely absent in cell lines of the luminal A and B subtypes that express CDH1 but not VIM and the ERBB2-overexpressing subtype that does not express CDH1 and VIM (Figure 1A,B). The gene discussed is KRT16; the disease is carcinoma.