Like uveal melanoma, mucosal melanoma also harbors mutations in the GNAQ/GNA11 genes, albeit rare, as well as others that include KIT, CDK4, CCND1, CDKN2A, NF1, BRAF, NRAS, SF3B1, PTEN, TPR, SPRED1 and TTN genes [19,24,25,26,27,28,29,30,31]. The gene discussed is GNAQ; the disease is uveal melanoma.