KIR3DL1 and cancer: The expression of the inhibitory KIR family (KIR2DL1, KIR2DL3, KIR2DL4 and KIR3DL1) as well as the reduced expression of activating receptors such as DNAM-1, NKG2C, NKp46 and NKp30, are also associated with poor cancer prognosis [31].