We have also provided new insights into the spatial significance of various immune subpopulations in OCCC, whereby tumour-associated macrophages (TAM) and regulatory T cells are excluded from the vicinity of tumour cells in low-risk patients, and TAMs and cytotoxic T cells are also excluded from the vicinity of tumour cells in ARID1A-mutated OCCCs. The gene discussed is ARID1A; the disease is neoplasm.