ARID1A and neoplasm: Comparing the spatial locations of the immunosuppressive subpopulations with ARID1A mutation status highlighted that CD68 + cells were significantly more prevalent in the stroma compared to tumour in the mutant cases (n = 13, p = 0.0007), yet no significant difference between these two spatial locations was present in wild-type cases (n = 17, p = 0.1089, paired samples Wilcoxon signed rank test) (Figure 4E–H).