High expression levels of OBSCN correlated with gene expression profiles suggestive of dysfunctional T cells only in lung and breast cancers, and LIN9 only in colorectal and lung cancers, while the expression of SEC16B correlates with gene expression profiles suggestive of dysfunctional T cells in breast, lung, and colorectal cancers (Figure 6C). This evidence concerns the gene SEC16B and breast carcinoma.