A multivariate analysis confirmed that age, CEA, and CRP were extracted as independent factors for predicting malignant tumors (hazard ratio (HR): 22.15, 95% confidence interval (CI): 5.02–97.6, p < 0.001; HR: 4.49, 95% CI: 1.26–15.99, p = 0.020; HR: 11.18, 95% CI: 2.80–44.64, p = 0.001, respectively). The gene discussed is CRP; the disease is cancer.