In addition, although combinational effects of an HDACi and CDDP in EOC cells have been tested (e.g., [36,60,61,62]) and reagents co-targeting CSC and non-CSC cell populations in cancer cell lines or mouse models have been reported (e.g., [57,58]), these studies did not test the effect in clearly defined CSC and non-CSC populations or were not linked to ZIP4. The gene discussed is SLC39A4; the disease is cancer.