For example, addition of CDDP increased tumor volumes on the ovaries and fallopian tubes as shown in the representative photos in Figure 6C. More dramatically, HDAC4-KD resulted in large tumors (10–15 mm in diameter) in the absence or presence of CDDP, around ovaries and fallopian tubes (Figure 6C), which was not observed in the LMK-235 groups, suggesting that there are differences between genetic depletion of the HDAC4 gene and pharmacological inhibition of HDAC4 and/or HDAC5. Here, HDAC5 is linked to neoplasm.