SNAI1 and colorectal cancer: In colorectal cancer, the main transcription factors regulating EMT include the Snail family (SNAI1 and SNAI2), the zinc finger E-box binding homeobox (ZEB) family, and the Twist bHLH transcription factor family, as well as the forkhead box family (FOXQ1, FOXC2, and FOXM1) and the prospero homeobox member PROX1 [105,106].