In TC, 75 blood samples of 11 female and 64 male patients with HNSCC, more specifically, 9 laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC), 56 oropharyngeal squamous cell carcinoma (OPSCC), 8 oral squamous cell carcinoma (OSCC) and 2 with cancer of another head and neck side, served for measurements of VEGF concentrations in pretherapeutic plasma and serum. The gene discussed is VEGFA; the disease is hypopharynx squamous cell carcinoma.