In an immunocompetent melanoma mouse model, CD103+CD141+ cDC1 that carry TAA migrate to draining lymph nodes (dLN) in a C-C motif chemokine receptor 7 (CCR7)-dependent manner and present TAA to naïve CD8+ T cells residing in dLN, leading to T cell priming [82]. This evidence concerns the gene CD8A and melanoma.