These include diseases related to mutations in the DNA damage response (DDR) and in the DNA repair pathways, such as Fanconi anemia [38] and ERCC6L2-associated bone marrow failure syndrome [39]; telomere maintenance, such as in dyskeratosis congenita or telomeropathies [40,41]; TP53 loss-of-function in Li-Fraumeni syndrome [42]; and two diseases due to inherited GATA-binding protein 2 (GATA2) mutations, MonoMAC syndrome [43] and Emberger syndrome [44]. The gene discussed is GATA2; the disease is bone marrow failure syndrome.