GFI1 and myeloid neoplasm: Allelic variants can also predispose to myeloid neoplasms, as in the case of GFI1. GFI1 is expressed in HSCs, as well as in lymphoid and myeloid precursors, where it regulates important myeloid genes, such as HOXA9, PBX1, MEIS1, CSF1, and CSFR1 [93].