ccRCC samples had a shorter NN distance from αSMA+ to Ki-67+ cells, compared with normal kidney samples (13 vs. 31 μm, respectively; p < 0.001), and longer NN distance from αSMA+ to caspase-3+ cells (32 vs. 9 μm, respectively; p < 0.001) (Figure 6A(iii)). This evidence concerns the gene ACTA1 and nonpapillary renal cell carcinoma.