Approximately 40% of TNBC expresses PD-L1 in TILs, and PD-L1 positive tumors (PD-L1 positivity is defined by PD-L1 expression on tumor-infiltrating immune cells covering ≥1% of the tumor area) tend to respond favorably to treatment with anti-PD-L1 therapy [102,103,104]. This evidence concerns the gene CD274 and neoplasm.