The following treatments have been evaluated and showed an inhibition of tumor growth capacity in meningioma flank models: Verapamil [27], CREB-binding protein inhibitor ICG 001 [28], Irinotecan [25], Imatinib [29], fatty acid synthase inhibitors [30], farnesyl thiosalicylic acid [31], Siomycin 1 [32], Mifepristone [33], Pegvisomant [23], and Celecoxib [34]. The gene discussed is CREB1; the disease is meningioma.