Similarly, when we treated GC resistant ALL-SIL and MOLT-4 cell lines with the AS1517499 STAT6 inhibitor, alone or in combination with dexamethasone, we observed that cell proliferation, measured by MTT assay and EdU staining, was significantly reduced by the combined treatments in both cell lines (Figure 4E,F). Here, STAT6 is linked to acute lymphoblastic leukemia.