When prostate cancer and benign prostatic hyperplasia PSA were compared, BPH patients’ glycoproteins contained predominantly terminally sialylated, complex-type biantennary N-glycans, whereas PSA from patients with prostate cancer presented an increased amount of similar biantennary complex-type glycans, but with one LacdiNAc unit, only partially sialylated [109]. Here, KLK3 is linked to Familial prostate cancer.