Consequently, breast tumors can be categorized into four different groups: (1) hormone receptors positive with HER2 receptor-negative (Luminal A); (2) hormone receptors negative with HER2 receptor-positive (HER2 enriched); (3) positive for hormone receptors and HER2 receptor (Luminal B), and (4) triple-negative tumors, which lack the expression of any of the receptors mentioned above [1]. The gene discussed is NR4A1; the disease is breast neoplasm.