The immunofluorescence results showed that the infiltration of Tfh cells in the tumor tissues of PDAC (Figure 1F–H), and in patients with high infiltration of functional Tfh cells (CD4+ CXCR5+ CXCL13+), resulted in longer OS and PFS (Figure 1I), indicating a positive correlation between functional infiltrating Tfh cells and patient survival. This evidence concerns the gene CXCL13 and neoplasm.