Finally, we wanted to determine whether conditional loss of Brca2 exon 11 impacted HR events by reducing RAD51-dependent HR (e.g., gene conversions) while concomitantly increasing SSA events, as has been reported using cell line-based assays (e.g., mouse embryonic stem cells, V-C8 Chinese hamster ovary cells and CAPAN-1 pancreatic carcinoma cells) [11,12,40]. The gene discussed is RAD51; the disease is exocrine pancreatic carcinoma.