The anti-MM effect was mediated, at least in part, by upregulation of pro-apoptotic BCL2 Binding Component 3 (BBC3)/PUMA protein, coupled with modulation of drug influx-efflux transporters Solute Carrier Family 7 Member 5 (SLC7A5)/LAT1 and the ATP-Binding cassette (ABC) transporter ABCC1/MRP1. This evidence concerns the gene ABCC1 and Miyoshi myopathy.