The AUCs of each serum protein used to diagnose HCC were 0.619, 0.748, 0.790, 0.652, 0.733, and 0.610, corresponding to ANAX5, CCT8, CFL1, ENO1, HSPB1, and TPM4, respectively (Figure 4b). The gene discussed is HSPB1; the disease is hepatocellular carcinoma.