The AUCs of each serum protein used to diagnose HCC were 0.619, 0.748, 0.790, 0.652, 0.733, and 0.610, corresponding to ANAX5, CCT8, CFL1, ENO1, HSPB1, and TPM4, respectively (Figure 4b). Here, ENO1 is linked to hepatocellular carcinoma.