CCT8 and hepatocellular carcinoma: Figure 4c (right panel) displays serum exosomal mRNA expression levels of CCT8 and CFL1. Concordant with serum protein levels, mRNA expression of serum exosomal CCT8 and CFL1 was significantly higher in HCC patients. Figure 4c (right panel) demonstrates the AUC of HCC diagnosis according to serum exosomal CCT8 and CFL1 expression values.