The AUCs of each serum protein used to diagnose HCC were 0.619, 0.748, 0.790, 0.652, 0.733, and 0.610, corresponding to ANAX5, CCT8, CFL1, ENO1, HSPB1, and TPM4, respectively (Figure 4b). This evidence concerns the gene CCT8 and hepatocellular carcinoma.