In this prospective study, the authors found that a deep learning approach may aid in the diagnosis of aggressive forms of prostate cancer, with an accuracy of 55% and precision of 93% using total PSA (tPSA), free PSA (fPSA), isoform-2 of proPSA (p2PSA), and PSAD [1]. This evidence concerns the gene KLK3 and prostate carcinoma.