CRP and infection: Our analysis echoes these observations and found that the patients with low Factor 3 levels (≤0.67) had higher CRP values (p = 0.037) and higher incidences of Grade 3/4 toxicities including infection (p = 0.043), and neutropenia (p = 0.012) and required longer RT days (p = 0.031) than those with high Factor 3 level (>0.67) (Table S2).