SLC10A1 and infection: When HBV infects hepatocytes, amino acids (aa) 2–47 (genotype D) in the preS1 are critical for the interaction of a viral particle with an HBV receptor, sodium taurocholate cotransporting polypeptide (NTCP), while a short and highly conserved motif (NPLGFFP at aa positions 9–15 in genotype D) is essential for attachment and subsequent infection [12,13].