FOXP3 and neoplasm: Interestingly, the infiltration of FOXP3+ cells was not associated with ECT local response, however, it was significantly associated to the development of visceral metastasis [178], corroborating similar results obtained by Ursic and colleagues (2021) in three different tumor models treated by ECT, where the more immunogenic CT26 tumors had better outcomes when compared with less immunogenic 4T1 and B16F10 tumors [179].