For example, some in vitro and in vivo studies have shown that treatment of cancer cells with albumin-NAMI-A or transferrin-NAMI-A adducts (NAMI-A: (ImH)[trans-RuCl(4)(dmso)(Im)], Im is imidazole), resulting in a significant reduction in biological activity compared with the parent ruthenium complex [23]. Here, ALB is linked to cancer.