NUCLEOLIN and cancer: In this case, liposomes prepared from cell membranes of red blood cells from rabbit, constituted of cholesterol, phospholipids, and α-Gal glycolipids, were functionalized (through cholesterol modification) with the AS1411 [76] The resulting liposome was able to recognize simultaneously anti-Gal antibodies and NCL overexpressed by tumor cells, followed by activating immune system to attack cancer cells.