Interestingly, MID1 binds to multiple CAG-repeat mRNAs regardless of the repeat-flanking sequences so that translation induction by MID1 occurs in cell models of multiple CAG-repeat diseases, such as HD and spinocerebellar ataxia types 2 (SCA2), 3 (SCA3) and 7 (SCA7) [67]. Here, MID1 is linked to Huntington disease.