GSTM1 and anemia: The current WHO cutoff levels were derived from mainly White adults37 but were validated in a multiethnic sample from a single country (US).22,23 The results of our multinational pooled fifth percentile Hb estimates were consistent with several studies10,12,13,14,15,38 that have called for a downward revision of the Hb cutoffs by approximately 1.0 g/dL for a variety of reasons, including a recent 2021 publication by Sachdev et al38 that suggests the use of lower Hb cutoffs to define anemia in children using data from the 2016 India Comprehensive National Nutrition Survey.