This hypothesis might also be indirectly supported by the fact that, in our study, the calculated ratios between some conjugated and unconjugated BAs were significantly higher in patients with T2DM than in those without (e.g., GCA+TCA/CA ratio: 9.7 ± 14.9 vs. 6.5 ± 14.5; and GDCA+TDCA/DCA ratio: 1.7 ± 2.6 vs. 0.8 ± 0.7, respectively, p = 0.001 by the Mann–Whitney test). Here, GNAT3 is linked to type 2 diabetes mellitus.