PDE4A and hepatocellular carcinoma: Interestingly, among other candidate genes, some genes are related to the progression of HCC, including, GATAD1 [44,45], FOXK1 [46], RALGAPA2 [47], PDE4A [48], TRIP6 [49], SPTBN1 [53], PTP4A3 [54], TRIM4 [56], and LMNB1 [60].