Moreover, SUV39H2 has been connected with cancer through its regulatory effect on LSD1 [70] and several cancer relevant genes which mainly act as tumor suppressor genes have been shown to be repressed by SUV39H2 overexpression including FAS, P16, P21 and Twist1, while oncogenes like PSA and C-myc are overexpressed [51]. The gene discussed is SUV39H2; the disease is neoplasm.