RIPK2 and colorectal carcinoma: It was shown that in TNBC, higher expression of RIPK2 is associated with increased recurrence; hence, further studies should be conducted to determine the role of RIPK2 in metastasis and recurrence in CRC, to see if it differs depending on the site of the tumor, and to assess its status as a potential target for therapy in metastatic CRC [13].