ODC1 and human African trypanosomiasis: Eflornithine, an inhibitor of ornithine decarboxylase [20], is a multifunctional drug as it is used topically (15% eflornithine cream) against unwanted facial hair (hirsutism) [21], as a treatment for malignant gliomas [22], and as an intravenous cocktail in combination with nifurtimox, approved by the EMA against African trypanosomiasis (sleeping sickness) caused by Trypanosoma brucei gambiense [23,24].