CAD: coronary artery disease; ACS: acute coronary disease; FH: familial hypercholesterolemia; AMI: acute myocardial infarction; HC: hypercholesterolemia (animal model); APOA-I: apolipoprotein A-I; ABCA1: ATP-binding cassette A1; LCAT: lecithin cholesteryl acetyltransferase; CETP: cholesteryl ester transfer protein; SCARB1: scavenger receptor class B member 1; PON1: paraoxonase 1; APOM: apolipoprotein M; SDMA: symmetric dimethylarginine; LBP: lipopolysaccharide-binding protein; SAA: serum amyloid A; ApoE: apolipoprotein E. The gene discussed is APOE; the disease is coronary artery disorder.