ERBB2 and breast cancer: For example, many human tumors, such as non-small cell lung cancer, squamous cell carcinoma of the head and neck, glioblastoma, pancreatic cancer, ovarian cancer, breast cancer, and prostate cancer were found to closely relate to the over-activation of human epidermal growth factor receptor 2 (Her2), a sub-family of ErbB (erythroblastic oncogene B) protein tyrosine kinases [8,10,11,12,13,14,15].