For the TH 1-related cytokines, the amounts of IFN-γ in both CRSwNP groups were higher than in the control 1 group; and there were no significant differences among the CRSwNP(I) and CRSwNP(II) groups compared to the control 2 group; however, the values of IL-2 and IL-12 fell below the detectable range in all groups (data not shown). This evidence concerns the gene IFNG and chronic rhinosinusitis with nasal polyps.