The levels of TH 2-associated cytokines, such as IL-5, IL-6, and IL-13 in the CRSwNP(I) and CRSwNP(II), were significantly higher than in the two control groups, and there were significant differences between the CRSwNP(I) and CRSwNP(II) groups. Here, IL6 is linked to chronic rhinosinusitis with nasal polyps.