The levels of TH 2-associated cytokines, such as IL-5, IL-6, and IL-13 in the CRSwNP(I) and CRSwNP(II), were significantly higher than in the two control groups, and there were significant differences between the CRSwNP(I) and CRSwNP(II) groups. The gene discussed is IL5; the disease is chronic rhinosinusitis with nasal polyps.