Data indicated that the p-JAK2 was significantly expressed in the epithelial basal layer of patients with CRSwNP(I); while p-JAK2 was highly expressed not only in both epithelial superficial and basal layer but also in inflammatory cells of patients with CRSwNP(II) (Figure 1B). This evidence concerns the gene JAK2 and chronic rhinosinusitis with nasal polyps.