The NQO1 gene polymorphism with the TT genotype was found in 12.7% of the patients with esophageal, 16.8% with stomach, 13.5% with colorectal, 9.7% with rectal, 17.7% with lung, 14.3% with breast, and 16.1% with prostate cancers and in 15.7% of patients with lymphoma. This evidence concerns the gene NQO1 and Familial prostate cancer.