The most common cytogenetic aberration in MM-EMD is 1q21 gain followed by del(13q) or del(17p) and C-MYC amplification [18,19], while in pEMP del(13q) and rearrangements of immunoglobulin heavy chain gene locus at 14q32 are prevailing [20]. The gene discussed is MYC; the disease is Miyoshi myopathy.