The SCN5A gene encodes the hNaV1.5 α-subunit, and mutations in SCN5A are associated with inherited susceptibility to ventricular arrhythmia, such as Brugada syndrome, long QT syndrome class 3 (LQT-3), or atrial fibrillation [15,16]. The gene discussed is SCN5A; the disease is Ventricular arrhythmia.