In an ob/ob mice NASH model, supplementation with green tea extracts (0.5% and 1% in diet, 6 weeks) showed inhibitive effects on liver steatosis, NASH, and damaged liver function, which may be associated with the lowered hepatic NADPH activity, myeloperoxidase (MPO) expression, and ROS generation, along with reduced lipid peroxidation [118]. This evidence concerns the gene MPO and metabolic dysfunction-associated steatohepatitis.