Similar to the non-astrocytic tauopathies and other neurodegenerative disorders, ARTAG has been observed frequently in the astrocytic tauopathies, specifically in FTLD-tau.The prevalence of ARTAG in primary FTLD-tau is high and has been reported in up to 100% of PSP, CBD and AGD cases although there appears to be a lower incidence of ARTAG in PiD [65,78]. The gene discussed is MAPT; the disease is argyrophilic grain disease.