MAPT and progressive supranuclear palsy: In FTLD-tau, pathology occurs in neurons, oligodendroglia and astrocytes, predominantly as 4R tau protein aggregates in progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), globular glial tauopathy (GGT) and argyrophilic grain disease (AGD) and 3R tau aggregates in Pick’s disease (PiD) [52,53].