Mean age at cancer diagnosis in each family was 51.5 and 56.0 years for BC and OC, respectively, in female relatives of VEO cancer BRCA2 families, and was 47.7 and 61.0 years, respectively, for BC and OC in no VEO cancer BRCA2 families (not represented, insufficient data for Wilcoxon–Mann–Withney test, details shown in Supplementary Table S2). This evidence concerns the gene BRCA2 and breast cancer.