The corresponding ovarian cancer risks were 14% (95% CI, 2% to 24%), 33% (8% to 50%), and 20% (2% to 35%) in carriers of the 185delAG, 5382insC in BRCA1 and 6174delT mutations in BRCA2, respectively [63]. The gene discussed is BRCA2; the disease is ovarian carcinoma.