The differential expression analysis also showed the upregulation of ACE2 TMPRSS2 and FURIN at day 16 post-infection, as shown in the heatmap in Figure 1A. We concluded that the characteristic patterns of expression of FURIN, ACE2 and TMPRSS2 might provide important insights into the dynamics of SARS-CoV-2 infection. This evidence concerns the gene ACE2 and infection.